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Understanding protein domain-swapping using structure-based models of protein folding
In domain-swapping, two or more identical protein monomers exchange structural elements and fold into dimers or multimers whose units are structurally similar to the original monomer. Domain-swapping is of biotechnological interest because inhibiting domain-swapping can reduce disease-causing fibril...
Autores principales: | Mascarenhas, Nahren Manuel, Gosavi, Shachi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127520/ https://www.ncbi.nlm.nih.gov/pubmed/27867057 http://dx.doi.org/10.1016/j.pbiomolbio.2016.09.013 |
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