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Porcine reproductive and respiratory syndrome virus activates the transcription of interferon alpha/beta (IFN-α/β) in monocyte-derived dendritic cells (Mo-DC)

Porcine reproductive and respiratory syndrome virus (PRRSV) is known to be a poor inducer of interferon alpha/beta (IFN-α/β), which may contribute to the delayed development of adaptive immunity and the resultant viral persistence. However, the exact mechanism by which PRRSV inhibits the induction o...

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Detalles Bibliográficos
Autores principales: Zhang, Hanmo, Guo, Xueshui, Nelson, Eric, Christopher-Hennings, Jane, Wang, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127654/
https://www.ncbi.nlm.nih.gov/pubmed/22592217
http://dx.doi.org/10.1016/j.vetmic.2012.04.025