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Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits

Severe acute respiratory syndrome is a highly infectious upper respiratory tract disease caused by SARS-CoV, a previously unidentified human coronavirus. SARS-3CL(pro) is a viral cysteine protease critical to the pathogen’s life cycle and hence a therapeutic target of importance. The recently elucid...

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Detalles Bibliográficos
Autores principales: Mukherjee, Prasenjit, Desai, Prashant, Ross, Larry, White, E. Lucile, Avery, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127700/
https://www.ncbi.nlm.nih.gov/pubmed/18343121
http://dx.doi.org/10.1016/j.bmc.2008.01.011