Cargando…
Structure-based virtual screening against SARS-3CL(pro) to identify novel non-peptidic hits
Severe acute respiratory syndrome is a highly infectious upper respiratory tract disease caused by SARS-CoV, a previously unidentified human coronavirus. SARS-3CL(pro) is a viral cysteine protease critical to the pathogen’s life cycle and hence a therapeutic target of importance. The recently elucid...
Autores principales: | Mukherjee, Prasenjit, Desai, Prashant, Ross, Larry, White, E. Lucile, Avery, Mitchell A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127700/ https://www.ncbi.nlm.nih.gov/pubmed/18343121 http://dx.doi.org/10.1016/j.bmc.2008.01.011 |
Ejemplares similares
-
Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PL(PRO) and 3CL(PRO) proteases
por: Jade, Dhananjay, et al.
Publicado: (2021) -
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease M(pro) by virtual screenings and hit optimization
por: Mercorelli, Beatrice, et al.
Publicado: (2022) -
Hierarchical virtual screening for the discovery of new molecular scaffolds in antibacterial hit identification
por: Ballester, Pedro J., et al.
Publicado: (2012) -
Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
por: Atanasova, Mariyana, et al.
Publicado: (2022) -
QM/QM studies for Michael reaction in coronavirus main protease (3CL(Pro))
por: Taranto, Alex G., et al.
Publicado: (2008)