Cargando…
Infection of Human Immunodeficiency Virus and Intracellular Viral Tat Protein Exert a Pro-survival Effect in a Human Microglial Cell Line
The interaction of human immunodeficiency virus type 1 (HIV-1) with CD4+ T lymphocytes is well studied and typically results in virally induced cytolysis. In contrast, relatively little is known concerning the interplay between HIV-1 and microglia. Recent findings suggest that, counter-intuitively,...
Autores principales: | Chugh, Pauline, Fan, Shongshan, Planelles, Vicente, Maggirwar, Sanjay B., Dewhurst, Stephen, Kim, Baek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127718/ https://www.ncbi.nlm.nih.gov/pubmed/17157319 http://dx.doi.org/10.1016/j.jmb.2006.11.011 |
Ejemplares similares
-
Ibudilast, a Pharmacologic Phosphodiesterase Inhibitor, Prevents Human Immunodeficiency Virus-1 Tat-Mediated Activation of Microglial Cells
por: Kiebala, Michelle, et al.
Publicado: (2011) -
Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy
por: Chugh, Pauline, et al.
Publicado: (2008) -
Human immunodeficiency virus-1 Tat exerts its neurotoxic effects by downregulating Sonic hedgehog signaling
por: khan, Irfan A., et al.
Publicado: (2022) -
Nuclear Factor-Kappa B Family Member RelB Inhibits Human Immunodeficiency Virus-1 Tat-Induced Tumor Necrosis Factor-Alpha Production
por: Kiebala, Michelle, et al.
Publicado: (2010) -
An Ounce of Tat Prevention Is Worth a Pound of Functional Cure
por: Planelles, Vicente
Publicado: (2015)