Immature and Mature Human Astrovirus: Structure, Conformational Changes, and Similarities to Hepatitis E Virus()

Human astroviruses (HAstVs) are a major cause of gastroenteritis. HAstV assembles from the structural protein VP90 and undergoes a cascade of proteolytic cleavages. Cleavage to VP70 is required for release of immature particles from cells, and subsequent cleavage by trypsin confers infectivity. We u...

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Detalles Bibliográficos
Autores principales: Dryden, Kelly A., Tihova, Mariana, Nowotny, Norbert, Matsui, Suzanne M., Mendez, Ernesto, Yeager, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127750/
https://www.ncbi.nlm.nih.gov/pubmed/22743104
http://dx.doi.org/10.1016/j.jmb.2012.06.029

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