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Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome

INTRODUCTION: Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures. METHODS: We...

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Autores principales: Thohar Arifin, Muhamad, Muttaqin, Zainal, Bakhtiar, Yuriz, Andar, Erie, Priambada, Dody, Kurnia, Happy, Risdianto, Ajid, Tsaniadi, Krisna, Kusnarto, Gunadi, Bunyamin, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127778/
https://www.ncbi.nlm.nih.gov/pubmed/32280261
http://dx.doi.org/10.2147/IJGM.S247438
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author Thohar Arifin, Muhamad
Muttaqin, Zainal
Bakhtiar, Yuriz
Andar, Erie
Priambada, Dody
Kurnia, Happy
Risdianto, Ajid
Tsaniadi, Krisna
Kusnarto, Gunadi
Bunyamin, Jacob
author_facet Thohar Arifin, Muhamad
Muttaqin, Zainal
Bakhtiar, Yuriz
Andar, Erie
Priambada, Dody
Kurnia, Happy
Risdianto, Ajid
Tsaniadi, Krisna
Kusnarto, Gunadi
Bunyamin, Jacob
author_sort Thohar Arifin, Muhamad
collection PubMed
description INTRODUCTION: Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures. METHODS: We observed 16 patients who underwent callosotomy (male to female ratio 7:9; adult to pediatric ratio 3:13). Initial seizure frequency was reported ranged from 1 to 2 attacks daily to very often (more than 20 episodes daily). RESULTS: Our observation showed that among patients with drop attacks, complete and >90% seizure freedom was reported by 4 and 6 of 13 patients, respectively (76.9% combined). CONCLUSION: Our observation showed that corpus callosotomy yielded good outcome in patients with intractable epilepsy in Indonesia. Our observation showed total callosotomy achieved complete seizure freedom better compared to partial callosotomy patients.
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spelling pubmed-71277782020-04-10 Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome Thohar Arifin, Muhamad Muttaqin, Zainal Bakhtiar, Yuriz Andar, Erie Priambada, Dody Kurnia, Happy Risdianto, Ajid Tsaniadi, Krisna Kusnarto, Gunadi Bunyamin, Jacob Int J Gen Med Original Research INTRODUCTION: Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures. METHODS: We observed 16 patients who underwent callosotomy (male to female ratio 7:9; adult to pediatric ratio 3:13). Initial seizure frequency was reported ranged from 1 to 2 attacks daily to very often (more than 20 episodes daily). RESULTS: Our observation showed that among patients with drop attacks, complete and >90% seizure freedom was reported by 4 and 6 of 13 patients, respectively (76.9% combined). CONCLUSION: Our observation showed that corpus callosotomy yielded good outcome in patients with intractable epilepsy in Indonesia. Our observation showed total callosotomy achieved complete seizure freedom better compared to partial callosotomy patients. Dove 2020-03-31 /pmc/articles/PMC7127778/ /pubmed/32280261 http://dx.doi.org/10.2147/IJGM.S247438 Text en © 2020 Thohar Arifin et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Thohar Arifin, Muhamad
Muttaqin, Zainal
Bakhtiar, Yuriz
Andar, Erie
Priambada, Dody
Kurnia, Happy
Risdianto, Ajid
Tsaniadi, Krisna
Kusnarto, Gunadi
Bunyamin, Jacob
Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title_full Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title_fullStr Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title_full_unstemmed Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title_short Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome
title_sort seizure outcomes in patients with complete versus anterior corpus callosotomy: analysis of outcome
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127778/
https://www.ncbi.nlm.nih.gov/pubmed/32280261
http://dx.doi.org/10.2147/IJGM.S247438
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