Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activity()

A reaction of 2-acetyl-3-acylaminobenzo[b]furans (9d–o) with Vilsmeier (VM) reagent afforded a mixture of (E)- and (Z)-{(E)-2-aralkenylbenzo[b]furo[3,2-d][1,3]oxazin-4-ylidene}acetaldehydes (5) with a characteristic exo-formylmethylene group on the oxazine ring. The Z-isomer was more stable than the...

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Detalles Bibliográficos
Autores principales: Tabuchi, Yukako, Ando, Yuko, Kanemura, Hidemi, Kawasaki, Ikuo, Ohishi, Takahiro, Koida, Masao, Fukuyama, Ryo, Nakamuta, Hiromichi, Ohta, Shunsaku, Nishide, Kiyoharu, Ohishi, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127799/
https://www.ncbi.nlm.nih.gov/pubmed/19406645
http://dx.doi.org/10.1016/j.bmc.2009.04.017

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