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Virus-induced neurobehavioral disorders: mechanisms and implications

One hypothesis for the etiology of neuropsychiatric disorders proposes that viral infection contributes to the induction of neuronal system dysfunction, resulting in a wide range of behavioral abnormalities. Recent research in molecular biology supports this hypothesis and refocuses on the role of v...

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Detalles Bibliográficos
Autor principal: Tomonaga, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128097/
https://www.ncbi.nlm.nih.gov/pubmed/15102360
http://dx.doi.org/10.1016/j.molmed.2003.12.001
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author Tomonaga, Keizo
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description One hypothesis for the etiology of neuropsychiatric disorders proposes that viral infection contributes to the induction of neuronal system dysfunction, resulting in a wide range of behavioral abnormalities. Recent research in molecular biology supports this hypothesis and refocuses on the role of viral infection in the development of psychiatric disorders. Viral infection can induce deleterious effects in the central nervous system by direct and/or indirect pathways. Understanding the mechanisms of glial cell dysfunction caused by persistent viral infection should lead to novel insights into the development of neurobehavioral disorders, including human mental illnesses, and to the possible development of treatments.
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spelling pubmed-71280972020-04-08 Virus-induced neurobehavioral disorders: mechanisms and implications Tomonaga, Keizo Trends Mol Med Article One hypothesis for the etiology of neuropsychiatric disorders proposes that viral infection contributes to the induction of neuronal system dysfunction, resulting in a wide range of behavioral abnormalities. Recent research in molecular biology supports this hypothesis and refocuses on the role of viral infection in the development of psychiatric disorders. Viral infection can induce deleterious effects in the central nervous system by direct and/or indirect pathways. Understanding the mechanisms of glial cell dysfunction caused by persistent viral infection should lead to novel insights into the development of neurobehavioral disorders, including human mental illnesses, and to the possible development of treatments. Elsevier Science Ltd. 2004-02 2004-01-07 /pmc/articles/PMC7128097/ /pubmed/15102360 http://dx.doi.org/10.1016/j.molmed.2003.12.001 Text en Copyright © 2003 Elsevier Science Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Tomonaga, Keizo
Virus-induced neurobehavioral disorders: mechanisms and implications
title Virus-induced neurobehavioral disorders: mechanisms and implications
title_full Virus-induced neurobehavioral disorders: mechanisms and implications
title_fullStr Virus-induced neurobehavioral disorders: mechanisms and implications
title_full_unstemmed Virus-induced neurobehavioral disorders: mechanisms and implications
title_short Virus-induced neurobehavioral disorders: mechanisms and implications
title_sort virus-induced neurobehavioral disorders: mechanisms and implications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128097/
https://www.ncbi.nlm.nih.gov/pubmed/15102360
http://dx.doi.org/10.1016/j.molmed.2003.12.001
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