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206: Transcriptional signatures of pathogenesis and successful type I interferon and ribavirin therapy in a rhesus macaque model of MERS-CoV infection

A novel betacoronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), emerged on the Arabian Peninsula in 2012. MERS-CoV was found to produce severe respiratory illness with case-fatality rates near 50%, and may be transmitted person-to-person in instances of close physical contact, such...

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Detalles Bibliográficos
Autores principales: Rasmussen, Angela L., Falzarano, Darryl, de Wit, Emmie, Feldmann, Friederike, Okumura, Atsushi, Scott, Dana P., Brining, Douglas, Bushmaker, Trent, Martellaro, Cynthia, Benecke, Arndt G., Munster, Vincent J., Feldmann, Heinz, Katze, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128186/
http://dx.doi.org/10.1016/j.cyto.2013.06.209