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Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in infants and is characterized by pulmonary infiltration of B cells in fatal cases. We analyzed the B cell compartment in human newborns and identified a population of neonatal regulatory B lymphocytes (nBreg...

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Detalles Bibliográficos
Autores principales: Zhivaki, Dania, Lemoine, Sébastien, Lim, Annick, Morva, Ahsen, Vidalain, Pierre-Olivier, Schandene, Liliane, Casartelli, Nicoletta, Rameix-Welti, Marie-Anne, Hervé, Pierre-Louis, Dériaud, Edith, Beitz, Benoit, Ripaux-Lefevre, Maryline, Miatello, Jordi, Lemercier, Brigitte, Lorin, Valerie, Descamps, Delphyne, Fix, Jenna, Eléouët, Jean-François, Riffault, Sabine, Schwartz, Olivier, Porcheray, Fabrice, Mascart, Françoise, Mouquet, Hugo, Zhang, Xiaoming, Tissières, Pierre, Lo-Man, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128247/
https://www.ncbi.nlm.nih.gov/pubmed/28228284
http://dx.doi.org/10.1016/j.immuni.2017.01.010