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COVID-19: A promising cure for the global panic

The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situat...

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Detalles Bibliográficos
Autores principales: Vellingiri, Balachandar, Jayaramayya, Kaavya, Iyer, Mahalaxmi, Narayanasamy, Arul, Govindasamy, Vivekanandhan, Giridharan, Bupesh, Ganesan, Singaravelu, Venugopal, Anila, Venkatesan, Dhivya, Ganesan, Harsha, Rajagopalan, Kamarajan, Rahman, Pattanathu K.S.M., Cho, Ssang-Goo, Kumar, Nachimuthu Senthil, Subramaniam, Mohana Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128376/
https://www.ncbi.nlm.nih.gov/pubmed/32278175
http://dx.doi.org/10.1016/j.scitotenv.2020.138277
Descripción
Sumario:The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.