Cargando…
Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties
System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2) is a transporter for non-cancer cells. In this s...
Autores principales: | Khunweeraphong, Narakorn, Nagamori, Shushi, Wiriyasermkul, Pattama, Nishinaka, Yumiko, Wongthai, Printip, Ohgaki, Ryuichi, Tanaka, Hidekazu, Tominaga, Hideyuki, Sakurai, Hiroyuki, Kanai, Yoshikatsu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V. Production and hosting by Elsevier B.V.
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128428/ https://www.ncbi.nlm.nih.gov/pubmed/22850614 http://dx.doi.org/10.1254/jphs.12124FP |
Ejemplares similares
-
Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB(0,+), LAT1 and LAT2
por: Wongthai, Printip, et al.
Publicado: (2015) -
Specific transport of 3‐fluoro‐l‐α‐methyl‐tyrosine by LAT1 explains its specificity to malignant tumors in imaging
por: Wei, Ling, et al.
Publicado: (2016) -
Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models
por: Shi, Zitong, et al.
Publicado: (2023) -
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation
por: Quan, Lili, et al.
Publicado: (2020) -
Expression of L-type amino acid transporter 1 (LAT1) as a prognostic and therapeutic indicator in multiple myeloma
por: Isoda, Atsushi, et al.
Publicado: (2014)