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108 : Preventing activation of the IFN inducible OAS-RNase L pathway by A-kinase anchoring protein 7 (AKAP7)

The 2′,5′-oligoadenylate (2-5A) synthetase (OAS)-RNase L system is an interferon inducible pathway that blocks virus infections by cleaving viral and cellular single-stranded RNA. Viral dsRNA, produced during infections by both RNA and DNA viruses, activates OAS (a pathogen recognition receptor) res...

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Detalles Bibliográficos
Autores principales:	Gusho, Elona, Jha, Babal K., Zhang, Rong, Weiss, Susan R., H. Silverman, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Ltd. 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128459/ http://dx.doi.org/10.1016/j.cyto.2013.06.111

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