Identification of Novel Small-Molecule Inhibitors of Severe Acute Respiratory Syndrome-Associated Coronavirus by Chemical Genetics

The severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infected more than 8,000 people across 29 countries and caused more than 900 fatalities. Based on the concept of chemical genetics, we screened 50,240 structurally diverse small molecules from which we identified 104 compounds w...

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Detalles Bibliográficos
Autores principales: Kao, Richard Y., Tsui, Wayne H.W., Lee, Terri S.W., Tanner, Julian A., Watt, Rory M., Huang, Jian-Dong, Hu, Lihong, Chen, Guanhua, Chen, Zhiwei, Zhang, Linqi, He, Tian, Chan, Kwok-Hung, Tse, Herman, To, Amanda P.C., Ng, Louisa W.Y., Wong, Bonnie C.W., Tsoi, Hoi-Wah, Yang, Dan, Ho, David D., Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128553/
https://www.ncbi.nlm.nih.gov/pubmed/15380189
http://dx.doi.org/10.1016/j.chembiol.2004.07.013

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