Cargando…

The antiviral effect of interferon-beta against SARS-Coronavirus is not mediated by MxA protein

Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus termed SARS-CoV. No antiviral treatment has been established so far. Interferons are cytokines which induce the synthesis of several antivirally active proteins in the cell. In this study, we demonstrated that multiplication o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spiegel, Martin, Pichlmair, Andreas, Mühlberger, Elke, Haller, Otto, Weber, Friedemann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128634/ https://www.ncbi.nlm.nih.gov/pubmed/15135736 http://dx.doi.org/10.1016/j.jcv.2003.11.013

Ejemplares similares

Vaccinia virus and Cowpox virus are not susceptible to the interferon-induced antiviral protein MxA
por: Lorenzo, María M., et al.
Publicado: (2017)

Interferon, Mx, and viral countermeasures
por: Haller, Otto, et al.
Publicado: (2007)

MxA mRNA Quantification and Disability Progression in Interferon Beta-Treated Multiple Sclerosis Patients
por: Serana, Federico, et al.
Publicado: (2014)

Baseline MxA mRNA Expression Predicts Interferon Beta Response in Multiple Sclerosis Patients
por: Matas, Elisabet, et al.
Publicado: (2014)

Polymorphisms of interferon-inducible genes OAS-1 and MxA associated with SARS in the Vietnamese population
por: Hamano, Emi, et al.
Publicado: (2005)

Rapid Reversible Osmoregulation of Cytoplasmic Biomolecular Condensates of Human Interferon-α-Induced Antiviral MxA GTPase
por: Sehgal, Pravin B., et al.
Publicado: (2022)

Prevalence of respiratory viruses and antiviral MxA responses in children with febrile urinary tract infection
por: Piri, Ruut, et al.
Publicado: (2020)

Detection of new biallelic polymorphisms in the human MxA gene
por: Duc, Tam Tran Thi, et al.
Publicado: (2012)

Interferon-α-induced cytoplasmic MxA structures in hepatoma Huh7 and primary endothelial cells
por: Davis, Deodate, et al.
Publicado: (2018)

In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein
por: Deeg, Christoph M., et al.
Publicado: (2017)

Pandemic Influenza A Viruses Escape from Restriction by Human MxA through Adaptive Mutations in the Nucleoprotein
por: Mänz, Benjamin, et al.
Publicado: (2013)

MxA as a clinically applicable biomarker for identifying systemic interferon type I in primary Sjögren's syndrome
por: Maria, Naomi I, et al.
Publicado: (2014)

Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
por: Götz, Veronika, et al.
Publicado: (2016)

Polymorphisms of the MxA and MxB genes are associated with biochemical indices and viral subtypes in Yunnan HCV patients
por: He, Mengzhu, et al.
Publicado: (2023)

Corrigendum: Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
por: Götz, Veronika, et al.
Publicado: (2016)

Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET
por: Chen, Yang, et al.
Publicado: (2017)

Association of functional polymorphisms in the MxA gene with susceptibility to enterovirus 71 infection
por: Zhang, Xiaoai, et al.
Publicado: (2013)

Lack of Induction by Rhinoviruses of Systemic Type I Interferon Production or Enhanced MxA Protein Expression During the Common Cold
por: Mäkelä, M. J., et al.
Publicado: (1999)

The Curious Case of Type I IFN and MxA: Tipping the Immune Balance in AIDS
por: Furuya, Andrea Kinga Marias, et al.
Publicado: (2014)

Blood MxA protein as a marker for respiratory virus infections in young children
por: Toivonen, Laura, et al.
Publicado: (2015)

MxA for differentiating viral and bacterial infections in adults: a prospective, exploratory study
por: Metz, Matthäus, et al.
Publicado: (2023)

Assessment of the Relation Between SNP in MxA Gene and the Responsiveness of Egyptian HCV Genotype 4 Patients to Pegylated Interferon and Ribavirin Treatment
por: Hassany, Mohamed, et al.
Publicado: (2017)

Structural analysis of tumor-related single amino acid mutations in human MxA protein
por: Hu, Jia-Li, et al.
Publicado: (2015)

Classical swine fever virus replicated poorly in cells from MxA transgenic pigs
por: Zhao, Yicheng, et al.
Publicado: (2016)

Deep mutational scanning identifies sites in influenza nucleoprotein that affect viral inhibition by MxA
por: Ashenberg, Orr, et al.
Publicado: (2017)

AB017. Increased dendritic cells and IFN-beta and MxA protein expression in spongiotic dermatitis differentiates dermatomyositis from eczema
por: Zeidi, Majid, et al.
Publicado: (2021)

The Human Interferon-Induced MxA Protein Inhibits Early Stages of Influenza A Virus Infection by Retaining the Incoming Viral Genome in the Cytoplasm
por: Xiao, Han, et al.
Publicado: (2013)

Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study
por: He, Jing, et al.
Publicado: (2006)

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses
por: Dornfeld, Dominik, et al.
Publicado: (2018)

MxA mRNA decrease preceding NAb detection in IFNβ‐treated MS patients
por: Libertinova, Jana, et al.
Publicado: (2017)

Genetic polymorphisms in the IFNL4, MxA, and MxB genes were associated with biochemical index of chronic HBV patients from Yunnan, China
por: Zheng, Kexi, et al.
Publicado: (2022)

Mx Is Not Responsible for the Antiviral Activity of Interferon-α against Japanese Encephalitis Virus
por: Zhou, Jing, et al.
Publicado: (2017)

Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon α
por: Zhijian, Yu, et al.
Publicado: (2010)

Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication
por: Alalem, Mai, et al.
Publicado: (2023)

MicroRNA-211 promotes non-small-cell lung cancer proliferation and invasion by targeting MxA
por: Kang, Mafei, et al.
Publicado: (2017)

Corrigendum: Influence of IL28B and MxA gene polymorphisms on HCV clearance in Han Chinese population
por: Zang, Feng, et al.
Publicado: (2019)

Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein
por: Fuchs, Jonas, et al.
Publicado: (2020)

The association between blood MxA mRNA and long-term disease activity in early multiple sclerosis
por: Coerver, Eline M. E., et al.
Publicado: (2022)

Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA
por: Petric, Philipp P., et al.
Publicado: (2022)

Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response
por: Kindler, E., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_19ipt3v16p058nnp5o86dq0mfk