MERS-CoV infection is associated with downregulation of genes encoding Th1 and Th2 cytokines/chemokines and elevated inflammatory innate immune response in the lower respiratory tract

MERS-CoV, a highly pathogenic virus in humans, is associated with high morbidity and case fatality. Inflammatory responses have a significant impact on MERS-CoV pathogenesis and disease outcome. However, CD4(+) T-cell induced immune responses during acute MERS-CoV infection are barely detectable, wi...

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Detalles Bibliográficos
Autores principales: Alosaimi, Bandar, Hamed, Maaweya E., Naeem, Asif, Alsharef, Ali A., AlQahtani, Saeed Y., AlDosari, Kamel M., Alamri, Aref A., Al-Eisa, Kholoud, Khojah, Taghreed, Assiri, Abdullah M., Enani, Mushira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128721/
https://www.ncbi.nlm.nih.gov/pubmed/31706200
http://dx.doi.org/10.1016/j.cyto.2019.154895

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