Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?

Among 78 laboratory-confirmed cases, we found two asymptomatic infections. One patient was discharged within 14 days after treatment. Another patient was discharged 25 days after treatment, and his RT-PCR test was still positive on the 15th day. We found that there may be virus carriers in the asymp...

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Autores principales: Wan, Ren, Mao, Zhi-Qun, He, Li-Yi, Hu, Yue-Chun, Wei-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128755/
https://www.ncbi.nlm.nih.gov/pubmed/32251796
http://dx.doi.org/10.1016/j.ijid.2020.03.041
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author Wan, Ren
Mao, Zhi-Qun
He, Li-Yi
Hu, Yue-Chun
Wei-Chen
author_facet Wan, Ren
Mao, Zhi-Qun
He, Li-Yi
Hu, Yue-Chun
Wei-Chen
author_sort Wan, Ren
collection PubMed
description Among 78 laboratory-confirmed cases, we found two asymptomatic infections. One patient was discharged within 14 days after treatment. Another patient was discharged 25 days after treatment, and his RT-PCR test was still positive on the 15th day. We found that there may be virus carriers in the asymptomatic population with an epidemiological contact history. After 14 days of isolation, those with asymptomatic infection may still carry the virus, which means a risk of transmission, presenting a new challenge for the management of home isolation.
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spelling pubmed-71287552020-04-08 Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient? Wan, Ren Mao, Zhi-Qun He, Li-Yi Hu, Yue-Chun Wei-Chen Int J Infect Dis Article Among 78 laboratory-confirmed cases, we found two asymptomatic infections. One patient was discharged within 14 days after treatment. Another patient was discharged 25 days after treatment, and his RT-PCR test was still positive on the 15th day. We found that there may be virus carriers in the asymptomatic population with an epidemiological contact history. After 14 days of isolation, those with asymptomatic infection may still carry the virus, which means a risk of transmission, presenting a new challenge for the management of home isolation. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-06 2020-04-03 /pmc/articles/PMC7128755/ /pubmed/32251796 http://dx.doi.org/10.1016/j.ijid.2020.03.041 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wan, Ren
Mao, Zhi-Qun
He, Li-Yi
Hu, Yue-Chun
Wei-Chen
Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title_full Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title_fullStr Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title_full_unstemmed Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title_short Evidence from two cases of asymptomatic infection with SARS-CoV-2: Are 14 days of isolation sufficient?
title_sort evidence from two cases of asymptomatic infection with sars-cov-2: are 14 days of isolation sufficient?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128755/
https://www.ncbi.nlm.nih.gov/pubmed/32251796
http://dx.doi.org/10.1016/j.ijid.2020.03.041
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