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Enhancing ergosterol production in Pichia pastoris GS115 by overexpressing squalene synthase gene from Glycyrrhiza uralensis

The present study was designed to determine the effects of copy number variations (CNVs) of squalene synthase 1(SQS1) gene on the mevalonate (MVA) pathway. SQS1 gene from G. uralensis (GuSQS1) was cloned and over-expressed in Pichia pastoris GS115. Six recombinant P. pastoris strains containing diff...

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Detalles Bibliográficos
Autores principales:	LIU, Ying, ZHU, Xiao-Qing, LI, Wen-Dong, WEN, Hao, LIU, Chun-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	China Pharmaceutical University. Published by Elsevier B.V. 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128851/ https://www.ncbi.nlm.nih.gov/pubmed/25986282 http://dx.doi.org/10.1016/S1875-5364(15)30024-8

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