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An Antiviral Mechanism of Nitric Oxide: Inhibition of a Viral Protease
Although nitric oxide (NO) kills or inhibits the replication of a variety of intracellular pathogens, the antimicrobial mechanisms of NO are unknown. Here, we identify a viral protease as a target of NO. The life cycle of many viruses depends upon viral proteases that cleave viral polyproteins into...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press.
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129050/ https://www.ncbi.nlm.nih.gov/pubmed/10023767 http://dx.doi.org/10.1016/S1074-7613(00)80003-5 |