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PKR inhibitors suppress endoplasmic reticulum stress and subdue glucolipotoxicity-mediated impairment of insulin secretion in pancreatic beta cells

Type 2 diabetes mellitus is characterized by insulin resistance and hypersecretion of insulin from the pancreas to compensate for decreased insulin sensitivity in the peripheral tissues. In later stages of the disease insulin-secreting beta cell degeneration commences and patients require insulin re...

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Detalles Bibliográficos
Autores principales:	YALÇIN, Abdullah, ŞARKICI, Gülçin, KOLAÇ, Umut Kerem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Scientific and Technological Research Council of Turkey 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129068/ https://www.ncbi.nlm.nih.gov/pubmed/32256145 http://dx.doi.org/10.3906/biy-1909-20

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