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The role of IL-12, IL-23 and IFN-γ in immunity to viruses

IL-12, IL-23 and IFN-γ form a loop and have been thought to play a crucial role against infectious viruses, which are the prototype of “intracellular” pathogens. In the last 10 years, the generation of knock-out (KO) mice for genes that control IL-12/IL-23-dependent IFN-γ-dependent mediated immunity...

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Detalles Bibliográficos
Autores principales: Novelli, Francesco, Casanova, Jean-Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129078/
https://www.ncbi.nlm.nih.gov/pubmed/15450252
http://dx.doi.org/10.1016/j.cytogfr.2004.03.009