The allele 4 of neck region liver‐lymph node‐specific ICAM‐3‐grabbing integrin variant is associated with spontaneous clearance of hepatitis C virus and decrease of viral loads

L‐SIGN is a C‐type lectin expressed on liver sinusoidal endothelial cells involved in the capture of hepatitis C virus and trans‐infection of adjacent hepatocyte cells. The neck region of L‐SIGN is highly polymorphic, with three to nine tandem repeats of 23 residues. This polymorphism is associated...

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Detalles Bibliográficos
Autores principales: Ezzikouri, S., Rebbani, K., Fakhir, F.‐Z., Alaoui, R., Nadir, S., Diepolder, H., Thursz, M., Khakoo, S. I., Benjelloun, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
VIROLOGY
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129123/
https://www.ncbi.nlm.nih.gov/pubmed/24283933
http://dx.doi.org/10.1111/1469-0691.12403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129123/
https://www.ncbi.nlm.nih.gov/pubmed/24283933
http://dx.doi.org/10.1111/1469-0691.12403

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