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The allele 4 of neck region liver‐lymph node‐specific ICAM‐3‐grabbing integrin variant is associated with spontaneous clearance of hepatitis C virus and decrease of viral loads
L‐SIGN is a C‐type lectin expressed on liver sinusoidal endothelial cells involved in the capture of hepatitis C virus and trans‐infection of adjacent hepatocyte cells. The neck region of L‐SIGN is highly polymorphic, with three to nine tandem repeats of 23 residues. This polymorphism is associated...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129123/ https://www.ncbi.nlm.nih.gov/pubmed/24283933 http://dx.doi.org/10.1111/1469-0691.12403 |