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A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates
Classification of pleural effusion (PE) is central to diagnosis. Traditional veterinary classification has distinguished between transudates, modified transudates and exudates. In human medicine PEs are divided into only two categories: transudates and exudates. The aim of this study was to evaluate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ESFM and AAFP. Published by Elsevier Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129129/ https://www.ncbi.nlm.nih.gov/pubmed/19539512 http://dx.doi.org/10.1016/j.jfms.2009.04.005 |
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author | Zoia, Andrea Slater, Linda A. Heller, Jane Connolly, David J. Church, David B. |
author_facet | Zoia, Andrea Slater, Linda A. Heller, Jane Connolly, David J. Church, David B. |
author_sort | Zoia, Andrea |
collection | PubMed |
description | Classification of pleural effusion (PE) is central to diagnosis. Traditional veterinary classification has distinguished between transudates, modified transudates and exudates. In human medicine PEs are divided into only two categories: transudates and exudates. The aim of this study was to evaluate, in 20 cats presented with PE, paired samples of serum and pleural fluid for the following parameters: Light's criteria (pleural fluid lactate dehydrogenase concentration (LDHp), pleural fluid/serum LDH ratio, pleural fluid/serum total protein ratio (TPr)), pleural fluid total protein, pleural fluid cholesterol concentration, pleural fluid/serum cholesterol ratio (CHOLr), serum-effusion cholesterol gradient (serum cholesterol minus PE cholesterol concentration (CHOLg)), PE total nucleated cells count (TNCCp) and pleural fluid glucose (GLUp). LDHp and TPr were found most reliable when distinguishing between transudates and exudates, with sensitivity of 100% and 91% and specificity of 100%, respectively. When conflict between the clinical picture and laboratory results exists, calculation of CHOLr, CHOLg and TNCCp measurement may help in the classification of the effusion. Measurement of serum albumin (in the case of a transudate) may provide additional information regarding the pathogenesis of the effusion. |
format | Online Article Text |
id | pubmed-7129129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | ESFM and AAFP. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71291292020-04-08 A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates Zoia, Andrea Slater, Linda A. Heller, Jane Connolly, David J. Church, David B. J Feline Med Surg Article Classification of pleural effusion (PE) is central to diagnosis. Traditional veterinary classification has distinguished between transudates, modified transudates and exudates. In human medicine PEs are divided into only two categories: transudates and exudates. The aim of this study was to evaluate, in 20 cats presented with PE, paired samples of serum and pleural fluid for the following parameters: Light's criteria (pleural fluid lactate dehydrogenase concentration (LDHp), pleural fluid/serum LDH ratio, pleural fluid/serum total protein ratio (TPr)), pleural fluid total protein, pleural fluid cholesterol concentration, pleural fluid/serum cholesterol ratio (CHOLr), serum-effusion cholesterol gradient (serum cholesterol minus PE cholesterol concentration (CHOLg)), PE total nucleated cells count (TNCCp) and pleural fluid glucose (GLUp). LDHp and TPr were found most reliable when distinguishing between transudates and exudates, with sensitivity of 100% and 91% and specificity of 100%, respectively. When conflict between the clinical picture and laboratory results exists, calculation of CHOLr, CHOLg and TNCCp measurement may help in the classification of the effusion. Measurement of serum albumin (in the case of a transudate) may provide additional information regarding the pathogenesis of the effusion. ESFM and AAFP. Published by Elsevier Ltd. 2009-10 2009-06-18 /pmc/articles/PMC7129129/ /pubmed/19539512 http://dx.doi.org/10.1016/j.jfms.2009.04.005 Text en Copyright © 2009 ESFM and AAFP. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Zoia, Andrea Slater, Linda A. Heller, Jane Connolly, David J. Church, David B. A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title | A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title_full | A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title_fullStr | A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title_full_unstemmed | A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title_short | A new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
title_sort | new approach to pleural effusion in cats: markers for distinguishing transudates from exudates |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129129/ https://www.ncbi.nlm.nih.gov/pubmed/19539512 http://dx.doi.org/10.1016/j.jfms.2009.04.005 |
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