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Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain

INTRODUCTION: In March 2020, Coronavirus Disease 2019 (COVID-19) arrived in Bolivia. Here, we report the main clinical findings, and epidemiological features of the first series of cases, and a cluster, confirmed in Bolivia. METHODS: For this observational, retrospective and cross-sectional study, i...

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Autores principales: Escalera-Antezana, Juan Pablo, Lizon-Ferrufino, Nicolas Freddy, Maldonado-Alanoca, Americo, Alarcón-De-la-Vega, Gricel, Alvarado-Arnez, Lucia Elena, Balderrama-Saavedra, María Alejandra, Bonilla-Aldana, D. Katterine, Rodríguez-Morales, Alfonso J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129170/
https://www.ncbi.nlm.nih.gov/pubmed/32247926
http://dx.doi.org/10.1016/j.tmaid.2020.101653
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author Escalera-Antezana, Juan Pablo
Lizon-Ferrufino, Nicolas Freddy
Maldonado-Alanoca, Americo
Alarcón-De-la-Vega, Gricel
Alvarado-Arnez, Lucia Elena
Balderrama-Saavedra, María Alejandra
Bonilla-Aldana, D. Katterine
Rodríguez-Morales, Alfonso J.
author_facet Escalera-Antezana, Juan Pablo
Lizon-Ferrufino, Nicolas Freddy
Maldonado-Alanoca, Americo
Alarcón-De-la-Vega, Gricel
Alvarado-Arnez, Lucia Elena
Balderrama-Saavedra, María Alejandra
Bonilla-Aldana, D. Katterine
Rodríguez-Morales, Alfonso J.
author_sort Escalera-Antezana, Juan Pablo
collection PubMed
description INTRODUCTION: In March 2020, Coronavirus Disease 2019 (COVID-19) arrived in Bolivia. Here, we report the main clinical findings, and epidemiological features of the first series of cases, and a cluster, confirmed in Bolivia. METHODS: For this observational, retrospective and cross-sectional study, information was obtained from the Hospitals and the Ministry of Health for the cases that were laboratory-diagnosed and related, during March 2020. rRT-PCR was used for the detection of the RNA of SARS-CoV-2 following the protocol Charité, Berlin, Germany, from nasopharyngeal swabs. RESULTS: Among 152 suspected cases investigated, 12 (7.9%) were confirmed with SARS-CoV-2 infected by rRT-PCR. The median age was 39 years (IQR 25–43), six of them male. Two cases proceed from Italy and three from Spain. Nine patients presented fever, and cough, five sore throat, and myalgia, among other symptoms. Only a 60 y-old woman with hypertension was hospitalized. None of the patients required ICU nor fatalities occurred in this group. CONCLUSIONS: This is the first report of surveillance of COVID-19 in Bolivia, with patients managed mainly with home isolation. Preparedness for a significant epidemic, as is going on in other countries, and the deployment of response plans for it, in the country is now taking place to mitigate the impact of the COVID-19 pandemic in the population.
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spelling pubmed-71291702020-04-08 Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain Escalera-Antezana, Juan Pablo Lizon-Ferrufino, Nicolas Freddy Maldonado-Alanoca, Americo Alarcón-De-la-Vega, Gricel Alvarado-Arnez, Lucia Elena Balderrama-Saavedra, María Alejandra Bonilla-Aldana, D. Katterine Rodríguez-Morales, Alfonso J. Travel Med Infect Dis Article INTRODUCTION: In March 2020, Coronavirus Disease 2019 (COVID-19) arrived in Bolivia. Here, we report the main clinical findings, and epidemiological features of the first series of cases, and a cluster, confirmed in Bolivia. METHODS: For this observational, retrospective and cross-sectional study, information was obtained from the Hospitals and the Ministry of Health for the cases that were laboratory-diagnosed and related, during March 2020. rRT-PCR was used for the detection of the RNA of SARS-CoV-2 following the protocol Charité, Berlin, Germany, from nasopharyngeal swabs. RESULTS: Among 152 suspected cases investigated, 12 (7.9%) were confirmed with SARS-CoV-2 infected by rRT-PCR. The median age was 39 years (IQR 25–43), six of them male. Two cases proceed from Italy and three from Spain. Nine patients presented fever, and cough, five sore throat, and myalgia, among other symptoms. Only a 60 y-old woman with hypertension was hospitalized. None of the patients required ICU nor fatalities occurred in this group. CONCLUSIONS: This is the first report of surveillance of COVID-19 in Bolivia, with patients managed mainly with home isolation. Preparedness for a significant epidemic, as is going on in other countries, and the deployment of response plans for it, in the country is now taking place to mitigate the impact of the COVID-19 pandemic in the population. Elsevier Ltd. 2020 2020-04-02 /pmc/articles/PMC7129170/ /pubmed/32247926 http://dx.doi.org/10.1016/j.tmaid.2020.101653 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Escalera-Antezana, Juan Pablo
Lizon-Ferrufino, Nicolas Freddy
Maldonado-Alanoca, Americo
Alarcón-De-la-Vega, Gricel
Alvarado-Arnez, Lucia Elena
Balderrama-Saavedra, María Alejandra
Bonilla-Aldana, D. Katterine
Rodríguez-Morales, Alfonso J.
Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title_full Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title_fullStr Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title_full_unstemmed Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title_short Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain
title_sort clinical features of the first cases and a cluster of coronavirus disease 2019 (covid-19) in bolivia imported from italy and spain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129170/
https://www.ncbi.nlm.nih.gov/pubmed/32247926
http://dx.doi.org/10.1016/j.tmaid.2020.101653
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