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Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins

The structures of snake venom metalloproteases (SVMPs) are proposed to be useful models to understand the structural and functional relationship of ADAM (a disintegrin and metalloprotease) which are membrane-anchored proteins involved in multiple human diseases. We have purified, sequenced and deter...

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Detalles Bibliográficos
Autores principales: Guan, Hong-Hsiang, Goh, King-Siang, Davamani, Fabian, Wu, Po-Long, Huang, Yen-Wei, Jeyakanthan, Jeyaraman, Wu, Wen-guey, Chen, Chun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129284/
https://www.ncbi.nlm.nih.gov/pubmed/19932752
http://dx.doi.org/10.1016/j.jsb.2009.11.009