Glycyrrhizin Inhibits Interleukin-8 Production and Nuclear Factor–κ B Activity in Lung Epithelial Cells, but Not Through Glucocorticoid Receptors

This study was designed to examine the glucocorticoid-like inhibitory effect of glycyrrhizin (GL) on interleukin (IL)-8 production in A549 lung epithelial cells. GL, as well as dexamethasone (DEX) inhibited both tumor necrosis factor (TNF)-α –and IL-1β –induced IL-8 production, mRNA expression, and...

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Detalles Bibliográficos
Autores principales: Takei, Hironori, Baba, Yuichiro, Hisatsune, Akinori, Katsuki, Hiroshi, Miyata, Takeshi, Yokomizo, Kazumi, Isohama, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. Production and hosting by Elsevier B.V. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129470/
https://www.ncbi.nlm.nih.gov/pubmed/18344608
http://dx.doi.org/10.1254/jphs.FP0072378

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