The role of IL-29 in immunity and cancer

Interleukin-29 (IL-29) is a new member of the recently discovered interferon λ (IFNλ) family. It is produced predominantly by maturing dendritic cells and macrophages. It has been implicated in numerous immunological responses and has shown antiviral activity similar to the Type I interferons, altho...

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Detalles Bibliográficos
Autores principales: Kelm, Noah E., Zhu, Ziwen, Ding, Vivi A., Xiao, Huaping, Wakefield, Mark R., Bai, Qian, Fang, Yujiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ireland Ltd. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129698/
https://www.ncbi.nlm.nih.gov/pubmed/27637354
http://dx.doi.org/10.1016/j.critrevonc.2016.08.002
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author Kelm, Noah E.
Zhu, Ziwen
Ding, Vivi A.
Xiao, Huaping
Wakefield, Mark R.
Bai, Qian
Fang, Yujiang
author_facet Kelm, Noah E.
Zhu, Ziwen
Ding, Vivi A.
Xiao, Huaping
Wakefield, Mark R.
Bai, Qian
Fang, Yujiang
author_sort Kelm, Noah E.
collection PubMed
description Interleukin-29 (IL-29) is a new member of the recently discovered interferon λ (IFNλ) family. It is produced predominantly by maturing dendritic cells and macrophages. It has been implicated in numerous immunological responses and has shown antiviral activity similar to the Type I interferons, although its target cell population is more limited than the Type I interferons. In recent years, the role of IL-29 in the pathogenesis of various cancers has also been extensively studied. In this review, we will discuss the recent advances of IL-29 in immunological processes and the pathogenesis of various cancer.
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spelling pubmed-71296982020-04-08 The role of IL-29 in immunity and cancer Kelm, Noah E. Zhu, Ziwen Ding, Vivi A. Xiao, Huaping Wakefield, Mark R. Bai, Qian Fang, Yujiang Crit Rev Oncol Hematol Article Interleukin-29 (IL-29) is a new member of the recently discovered interferon λ (IFNλ) family. It is produced predominantly by maturing dendritic cells and macrophages. It has been implicated in numerous immunological responses and has shown antiviral activity similar to the Type I interferons, although its target cell population is more limited than the Type I interferons. In recent years, the role of IL-29 in the pathogenesis of various cancers has also been extensively studied. In this review, we will discuss the recent advances of IL-29 in immunological processes and the pathogenesis of various cancer. Elsevier Ireland Ltd. 2016-10 2016-08-10 /pmc/articles/PMC7129698/ /pubmed/27637354 http://dx.doi.org/10.1016/j.critrevonc.2016.08.002 Text en © 2016 Elsevier Ireland Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kelm, Noah E.
Zhu, Ziwen
Ding, Vivi A.
Xiao, Huaping
Wakefield, Mark R.
Bai, Qian
Fang, Yujiang
The role of IL-29 in immunity and cancer
title The role of IL-29 in immunity and cancer
title_full The role of IL-29 in immunity and cancer
title_fullStr The role of IL-29 in immunity and cancer
title_full_unstemmed The role of IL-29 in immunity and cancer
title_short The role of IL-29 in immunity and cancer
title_sort role of il-29 in immunity and cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129698/
https://www.ncbi.nlm.nih.gov/pubmed/27637354
http://dx.doi.org/10.1016/j.critrevonc.2016.08.002
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