Myeloma-related disorder with leukaemic progression in a cat

A 10-year-old American Shorthair cat with nasal discharge, anorexia, and weight loss was found to have pancytopenia and hyperproteinaemia. Bone marrow aspiration revealed atypical plasma cells that totalled 50% of the nucleated bone marrow cells. The number of atypical plasma cells progressively inc...

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Autores principales: Takeuchi, Yoshinori, Iizuka, Haruna, Kanemitsu, Hiroyuki, Fujino, Yasuhito, Nakashima, Ko, Uchida, Kazuyuki, Ohno, Koichi, Nakayama, Hiroyuki, Tsujimoto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ISFM and AAFP. Published by Elsevier Ltd. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129832/
https://www.ncbi.nlm.nih.gov/pubmed/21036087
http://dx.doi.org/10.1016/j.jfms.2010.07.018
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author Takeuchi, Yoshinori
Iizuka, Haruna
Kanemitsu, Hiroyuki
Fujino, Yasuhito
Nakashima, Ko
Uchida, Kazuyuki
Ohno, Koichi
Nakayama, Hiroyuki
Tsujimoto, Hajime
author_facet Takeuchi, Yoshinori
Iizuka, Haruna
Kanemitsu, Hiroyuki
Fujino, Yasuhito
Nakashima, Ko
Uchida, Kazuyuki
Ohno, Koichi
Nakayama, Hiroyuki
Tsujimoto, Hajime
author_sort Takeuchi, Yoshinori
collection PubMed
description A 10-year-old American Shorthair cat with nasal discharge, anorexia, and weight loss was found to have pancytopenia and hyperproteinaemia. Bone marrow aspiration revealed atypical plasma cells that totalled 50% of the nucleated bone marrow cells. The number of atypical plasma cells progressively increased in the peripheral blood during the observation period of 64 days. The cat did not respond to treatments with melphalan, chlorambucil, and prednisolone, and died 71 days after the initial presentation. Clinical, cytological, histopathological, and immunohistochemical findings in this case supported the diagnosis of myeloma-related disorder (MRD) with leukaemic progression.
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spelling pubmed-71298322020-04-08 Myeloma-related disorder with leukaemic progression in a cat Takeuchi, Yoshinori Iizuka, Haruna Kanemitsu, Hiroyuki Fujino, Yasuhito Nakashima, Ko Uchida, Kazuyuki Ohno, Koichi Nakayama, Hiroyuki Tsujimoto, Hajime J Feline Med Surg Article A 10-year-old American Shorthair cat with nasal discharge, anorexia, and weight loss was found to have pancytopenia and hyperproteinaemia. Bone marrow aspiration revealed atypical plasma cells that totalled 50% of the nucleated bone marrow cells. The number of atypical plasma cells progressively increased in the peripheral blood during the observation period of 64 days. The cat did not respond to treatments with melphalan, chlorambucil, and prednisolone, and died 71 days after the initial presentation. Clinical, cytological, histopathological, and immunohistochemical findings in this case supported the diagnosis of myeloma-related disorder (MRD) with leukaemic progression. ISFM and AAFP. Published by Elsevier Ltd. 2010-12 2010-10-30 /pmc/articles/PMC7129832/ /pubmed/21036087 http://dx.doi.org/10.1016/j.jfms.2010.07.018 Text en Copyright © 2010 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Takeuchi, Yoshinori
Iizuka, Haruna
Kanemitsu, Hiroyuki
Fujino, Yasuhito
Nakashima, Ko
Uchida, Kazuyuki
Ohno, Koichi
Nakayama, Hiroyuki
Tsujimoto, Hajime
Myeloma-related disorder with leukaemic progression in a cat
title Myeloma-related disorder with leukaemic progression in a cat
title_full Myeloma-related disorder with leukaemic progression in a cat
title_fullStr Myeloma-related disorder with leukaemic progression in a cat
title_full_unstemmed Myeloma-related disorder with leukaemic progression in a cat
title_short Myeloma-related disorder with leukaemic progression in a cat
title_sort myeloma-related disorder with leukaemic progression in a cat
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129832/
https://www.ncbi.nlm.nih.gov/pubmed/21036087
http://dx.doi.org/10.1016/j.jfms.2010.07.018
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