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Nucleoside hydrolase DNA vaccine against canine visceral leishmaniasis
The Nucleoside Hydrolase (NH36) is the main marker of the FML complex of Leishmania donovani, antigen of the licensed Leishmune® vaccine for prophylaxis of canine visceral leishmaniasis. As a DNA vaccine in mice, it induces a TH1 immune response. We vaccinated mongrel dogs with the VR1012NH36 vaccin...
Autores principales: | Borja-Cabrera, GP, Santos, FB, Picillo, E, Gravino, AE, Manna, L, Palatnik-de-Sousa, CB |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129871/ https://www.ncbi.nlm.nih.gov/pubmed/32288909 http://dx.doi.org/10.1016/j.provac.2009.07.019 |
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