A Novel Therapeutic and Prophylactic Vaccine (HVJ-Envelope / Hsp65 DNA + IL-12 DNA) against Tuberculosis Using the Cynomolgus Monkey Model

We have developed a novel tuberculosis (TB) vaccine; a combination of the DNA vaccines expressing mycobacterial heat shock protein 65 (HSP65) and interleukin 12 (IL-12) delivered by the hemagglutinating virus of Japan (HVJ)-envelope and –liposome (HSP65 + IL-12/HVJ). An IL-12 expression vector (IL-1...

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Detalles Bibliográficos
Autores principales: Okada, M, Kita, Y, Nakajima, T, Kanamaru, N, Hashimoto, S, Nishida, Y, Nakatani, H, Takao, K, Kishigami, C, Nishimatsu, S, Sekine, Y, Inoue, Y, Nagasawa, T, Kaneda, Y, Yoshida, S, Matsumoto, M, Paul, Saunderson, Tan, E.V., Cruz, E.C.Dela, N. McMurray, D, Sakatani, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129898/
https://www.ncbi.nlm.nih.gov/pubmed/32288910
http://dx.doi.org/10.1016/j.provac.2010.03.007

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