Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()

The research aims was to determine the cytotoxic effects and the highest safe concentration of curcumin and PGV-0 on vero cells. This research also compare the effect of curcumin and PGV-0 against vero cells infected by Dengue virus (in vitro) in one and three days incubation period. The highest saf...

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Detalles Bibliográficos
Autores principales: Marbawati, Dewi, Umniyati, Sitti Rahmah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129986/
https://www.ncbi.nlm.nih.gov/pubmed/32288928
http://dx.doi.org/10.1016/j.proenv.2015.01.033
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author Marbawati, Dewi
Umniyati, Sitti Rahmah
author_facet Marbawati, Dewi
Umniyati, Sitti Rahmah
author_sort Marbawati, Dewi
collection PubMed
description The research aims was to determine the cytotoxic effects and the highest safe concentration of curcumin and PGV-0 on vero cells. This research also compare the effect of curcumin and PGV-0 against vero cells infected by Dengue virus (in vitro) in one and three days incubation period. The highest safe concentrations against vero cells from curcumin was 6.25 ppm and 1.5625 ppm for PGV-0. Immunocytochemistry test of curcumin and PGV-0 in both incubation period (one and three days) shows no significant difference (significant value 0.925), but RT-PCR result indicates that PGV - 0 have potential antiviral better than curcumin.
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spelling pubmed-71299862020-04-08 Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study() Marbawati, Dewi Umniyati, Sitti Rahmah Procedia Environ Sci Article The research aims was to determine the cytotoxic effects and the highest safe concentration of curcumin and PGV-0 on vero cells. This research also compare the effect of curcumin and PGV-0 against vero cells infected by Dengue virus (in vitro) in one and three days incubation period. The highest safe concentrations against vero cells from curcumin was 6.25 ppm and 1.5625 ppm for PGV-0. Immunocytochemistry test of curcumin and PGV-0 in both incubation period (one and three days) shows no significant difference (significant value 0.925), but RT-PCR result indicates that PGV - 0 have potential antiviral better than curcumin. Published by Elsevier B.V. 2015 2015-01-31 /pmc/articles/PMC7129986/ /pubmed/32288928 http://dx.doi.org/10.1016/j.proenv.2015.01.033 Text en Copyright © 2015 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Marbawati, Dewi
Umniyati, Sitti Rahmah
Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title_full Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title_fullStr Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title_full_unstemmed Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title_short Effects of Curcumin and Pentagamavunon-0 Against Dengue-2 Virus Infection in Vero Cells; an in Vitro Study()
title_sort effects of curcumin and pentagamavunon-0 against dengue-2 virus infection in vero cells; an in vitro study()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129986/
https://www.ncbi.nlm.nih.gov/pubmed/32288928
http://dx.doi.org/10.1016/j.proenv.2015.01.033
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