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Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study
A spontaneous neurological disease in cats characterized by behavioural and motor disturbances was investigated by clinical, morphological and immunological methods. Neuropathological examination showed a marked inflammatory reaction in the cerebral leptomeninges and the grey matter of the brain. In...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Published by Elsevier Ltd.
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130315/ https://www.ncbi.nlm.nih.gov/pubmed/1291589 http://dx.doi.org/10.1016/0021-9975(92)90015-M |
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author | Lundgren, A.-L. |
author_facet | Lundgren, A.-L. |
author_sort | Lundgren, A.-L. |
collection | PubMed |
description | A spontaneous neurological disease in cats characterized by behavioural and motor disturbances was investigated by clinical, morphological and immunological methods. Neuropathological examination showed a marked inflammatory reaction in the cerebral leptomeninges and the grey matter of the brain. In the white matter, the reaction was moderate. The changes consisted of perivascular cuffing by mononuclear cells and neuronal damage. The brain stem (thalamus, mesencephalon, caudal colliculus) was most severely affected. The spinal cord and its leptomeninges were involved to a lesser degree. The histopathological picture as well as the laboratory findings suggests a viral cause of the disease. The morphology of the disease and serological as well as immunohistochemical results indicate that this disorder is different from previously known feline viral encephalitides. |
format | Online Article Text |
id | pubmed-7130315 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1992 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71303152020-04-08 Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study Lundgren, A.-L. J Comp Pathol Article A spontaneous neurological disease in cats characterized by behavioural and motor disturbances was investigated by clinical, morphological and immunological methods. Neuropathological examination showed a marked inflammatory reaction in the cerebral leptomeninges and the grey matter of the brain. In the white matter, the reaction was moderate. The changes consisted of perivascular cuffing by mononuclear cells and neuronal damage. The brain stem (thalamus, mesencephalon, caudal colliculus) was most severely affected. The spinal cord and its leptomeninges were involved to a lesser degree. The histopathological picture as well as the laboratory findings suggests a viral cause of the disease. The morphology of the disease and serological as well as immunohistochemical results indicate that this disorder is different from previously known feline viral encephalitides. Published by Elsevier Ltd. 1992-11 2004-09-23 /pmc/articles/PMC7130315/ /pubmed/1291589 http://dx.doi.org/10.1016/0021-9975(92)90015-M Text en Copyright © 1992 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Lundgren, A.-L. Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title | Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title_full | Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title_fullStr | Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title_full_unstemmed | Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title_short | Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study |
title_sort | feline non-suppurative meningoencephalomyelitis. a clinical and pathological study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130315/ https://www.ncbi.nlm.nih.gov/pubmed/1291589 http://dx.doi.org/10.1016/0021-9975(92)90015-M |
work_keys_str_mv | AT lundgrenal felinenonsuppurativemeningoencephalomyelitisaclinicalandpathologicalstudy |