Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture

Two different strains of Aujeszky's disease virus (ADV) were inoculated into swine tracheal organ culture. Both viruses replicated in and destroyed the tracheal epithelium and epithelial cells. ADV antigen was first localized in ciliated epithelial cells by fluorescent antibody and immunoperoxi...

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Detalles Bibliográficos
Autores principales: Narita, M., Imada, T., Kobayashi, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130398/
https://www.ncbi.nlm.nih.gov/pubmed/1663139
http://dx.doi.org/10.1016/S0021-9975(08)80113-2
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author Narita, M.
Imada, T.
Kobayashi, M.
author_facet Narita, M.
Imada, T.
Kobayashi, M.
author_sort Narita, M.
collection PubMed
description Two different strains of Aujeszky's disease virus (ADV) were inoculated into swine tracheal organ culture. Both viruses replicated in and destroyed the tracheal epithelium and epithelial cells. ADV antigen was first localized in ciliated epithelial cells by fluorescent antibody and immunoperoxidase examinations. Corresponding to the distribution of ADV antigen, many ADV particles were observed in ciliated epithelial cells. Results demonstrated that the tracheal epithelium infected with ADV is reduced in its ciliary activity.
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spelling pubmed-71303982020-04-08 Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture Narita, M. Imada, T. Kobayashi, M. J Comp Pathol Article Two different strains of Aujeszky's disease virus (ADV) were inoculated into swine tracheal organ culture. Both viruses replicated in and destroyed the tracheal epithelium and epithelial cells. ADV antigen was first localized in ciliated epithelial cells by fluorescent antibody and immunoperoxidase examinations. Corresponding to the distribution of ADV antigen, many ADV particles were observed in ciliated epithelial cells. Results demonstrated that the tracheal epithelium infected with ADV is reduced in its ciliary activity. Published by Elsevier Ltd. 1991-11 2008-02-04 /pmc/articles/PMC7130398/ /pubmed/1663139 http://dx.doi.org/10.1016/S0021-9975(08)80113-2 Text en Copyright © 1991 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Narita, M.
Imada, T.
Kobayashi, M.
Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title_full Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title_fullStr Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title_full_unstemmed Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title_short Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture
title_sort pathogenesis of aujeszky's disease virus infection in swine tracheal organ culture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130398/
https://www.ncbi.nlm.nih.gov/pubmed/1663139
http://dx.doi.org/10.1016/S0021-9975(08)80113-2
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