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Amino acid substitution matrices from an information theoretic perspective

Protein sequence alignments have become an important tool for molecular biologists. Local alignments are frequently constructed with the aid of a “substitution score matrix” that specifies a score for aligning each pair of amino acid residues. Over the years, many different substitution matrices hav...

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Detalles Bibliográficos
Autor principal: Altschul, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130686/
https://www.ncbi.nlm.nih.gov/pubmed/2051488
http://dx.doi.org/10.1016/0022-2836(91)90193-A