AIDS-Myelopathy: A Neuropathological Study

Vacuolar myelopathy belongs to the AIDS-associated diseases. It is characterized by vacuolation and infiltration of the long tracts of the spinal cord by macrophages. The clinical and morphological findings of 8 AIDS-patients with vacuolar myelopathy are reported here. The syndrome developed during...

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Autores principales: Bergmann, M., Gullotta, F., Kuchelmeister, K., Masini, Tina, Angeli, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gustav Fischer Verlag · Stuttgart · Jena · New York. Published by Elsevier GmbH 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130719/
https://www.ncbi.nlm.nih.gov/pubmed/8516218
http://dx.doi.org/10.1016/S0344-0338(11)80117-2
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author Bergmann, M.
Gullotta, F.
Kuchelmeister, K.
Masini, Tina
Angeli, G.
author_facet Bergmann, M.
Gullotta, F.
Kuchelmeister, K.
Masini, Tina
Angeli, G.
author_sort Bergmann, M.
collection PubMed
description Vacuolar myelopathy belongs to the AIDS-associated diseases. It is characterized by vacuolation and infiltration of the long tracts of the spinal cord by macrophages. The clinical and morphological findings of 8 AIDS-patients with vacuolar myelopathy are reported here. The syndrome developed during the final stages of AIDS and was associated with HIV-encephalopathy in 5 cases. The vacuoles were mainly due to intramyelinic swelling and vacuolation. Vacuolated macrophages and axons contributed only to a minor degree. In one case only, HIV-antigens were detected immunohistochemically. The results are discussed in the light of modern pathogenetical concepts of HIV-related diseases.
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spelling pubmed-71307192020-04-08 AIDS-Myelopathy: A Neuropathological Study Bergmann, M. Gullotta, F. Kuchelmeister, K. Masini, Tina Angeli, G. Pathol Res Pract Article Vacuolar myelopathy belongs to the AIDS-associated diseases. It is characterized by vacuolation and infiltration of the long tracts of the spinal cord by macrophages. The clinical and morphological findings of 8 AIDS-patients with vacuolar myelopathy are reported here. The syndrome developed during the final stages of AIDS and was associated with HIV-encephalopathy in 5 cases. The vacuoles were mainly due to intramyelinic swelling and vacuolation. Vacuolated macrophages and axons contributed only to a minor degree. In one case only, HIV-antigens were detected immunohistochemically. The results are discussed in the light of modern pathogenetical concepts of HIV-related diseases. Gustav Fischer Verlag · Stuttgart · Jena · New York. Published by Elsevier GmbH 1993-02 2011-11-02 /pmc/articles/PMC7130719/ /pubmed/8516218 http://dx.doi.org/10.1016/S0344-0338(11)80117-2 Text en © 1993 Gustav Fischer Verlag · Stuttgart · Jena · New York Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Bergmann, M.
Gullotta, F.
Kuchelmeister, K.
Masini, Tina
Angeli, G.
AIDS-Myelopathy: A Neuropathological Study
title AIDS-Myelopathy: A Neuropathological Study
title_full AIDS-Myelopathy: A Neuropathological Study
title_fullStr AIDS-Myelopathy: A Neuropathological Study
title_full_unstemmed AIDS-Myelopathy: A Neuropathological Study
title_short AIDS-Myelopathy: A Neuropathological Study
title_sort aids-myelopathy: a neuropathological study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130719/
https://www.ncbi.nlm.nih.gov/pubmed/8516218
http://dx.doi.org/10.1016/S0344-0338(11)80117-2
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