Efficient Autoproteolytic Processing of the MHV-A59 3C-like Proteinase from the Flanking Hydrophobic Domains Requires Membranes

The replicase gene of the coronavirus MHV-A59 encodes a serine-like proteinase similar to the 3C proteinases of picornaviruses. This proteinase domain is flanked on both sides by hydrophobic, potentially membrane-spanning, regions. Cell-free expression of a plasmid encoding only the 3C-like proteina...

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Detalles Bibliográficos
Autores principales: Piñón, Josefina D., Mayreddy, Ravi R., Turner, Julie D., Khan, Farah S., Bonilla, Pedro J., Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1997
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130731/
https://www.ncbi.nlm.nih.gov/pubmed/9143287
http://dx.doi.org/10.1006/viro.1997.8503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130731/
https://www.ncbi.nlm.nih.gov/pubmed/9143287
http://dx.doi.org/10.1006/viro.1997.8503

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