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Efficient Autoproteolytic Processing of the MHV-A59 3C-like Proteinase from the Flanking Hydrophobic Domains Requires Membranes

The replicase gene of the coronavirus MHV-A59 encodes a serine-like proteinase similar to the 3C proteinases of picornaviruses. This proteinase domain is flanked on both sides by hydrophobic, potentially membrane-spanning, regions. Cell-free expression of a plasmid encoding only the 3C-like proteina...

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Detalles Bibliográficos
Autores principales:	Piñón, Josefina D., Mayreddy, Ravi R., Turner, Julie D., Khan, Farah S., Bonilla, Pedro J., Weiss, Susan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press. 1997
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130731/ https://www.ncbi.nlm.nih.gov/pubmed/9143287 http://dx.doi.org/10.1006/viro.1997.8503

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