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Successful cross-protective efficacy induced by heat-adapted live attenuated nephropathogenic infectious bronchitis virus derived from a natural recombinant strain
A natural recombinant nephropathogenic K40/09 strain of infectious bronchitis virus (IBV) was heat-adapted for possible future use as live attenuated vaccine. The K40/09 strain was selected during successive serial passages in specific-pathogen free (SPF) embryonated eggs at sub-optimal higher tempe...
Autores principales: | Lim, Tae-Hyun, Youn, Ha-Na, Yuk, Seong-Su, Kwon, Jung-Hoon, Hong, Woo-Tack, Gwon, Gyeong-Bin, Lee, Jung-Ah, Lee, Joong-Bok, Lee, Sang-Won, Song, Chang-Seon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130781/ https://www.ncbi.nlm.nih.gov/pubmed/26218899 http://dx.doi.org/10.1016/j.vaccine.2015.07.043 |
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