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Murine Coronavirus-Induced Apoptosis in 17Cl-1 Cells Involves a Mitochondria-Mediated Pathway and Its Downstream Caspase-8 Activation and Bid Cleavage

Mouse hepatitis virus (MHV) infection in murine 17Cl-1 cells results in apoptotic cell death. Inhibition of MHV-induced apoptosis by the pancaspase inhibitor Z-VAD-FMK promoted virus production late in infection, indicating that apoptosis could be a host response to limit the production of viral pro...

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Detalles Bibliográficos
Autores principales:	Chen, Chun-Jen, Makino, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science (USA). 2002
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131008/ https://www.ncbi.nlm.nih.gov/pubmed/12441076 http://dx.doi.org/10.1006/viro.2002.1626

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