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Characterization of coronavirus JHM variants isolated from wistar furth rats with a viral-induced demyelinating disease

Murine hepatitis virus (MHV) can cause neurological disease when inoculated intracerebrally (ic) into mice and rats. Specifically the JHM strain of MHV (MHV-JHM) generally causes an acute encephalitis when inoculated is into 2-day-old Wistar Furth rats. In contrast, JHM generally produces a chronic...

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Detalles Bibliográficos
Autores principales: Morris, Vincent L., Tieszer, Christina, MacKinnon, Joanne, Percy, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131095/
https://www.ncbi.nlm.nih.gov/pubmed/2538027
http://dx.doi.org/10.1016/0042-6822(89)90048-2