Sequence Analysis of the Nucleocapsid Protein Gene of Rat Coronavirus SDAV-681

The nucleotide sequence of the 3′-end of the genomic RNA of sialodacryoadenitis virus strain 681 (SDAV-681) was determined. A large open reading frame encoding a 454-amino-acid protein was identified as the nucleocapsid protein (N) gene, since the predicted protein is similar in size, chemical prope...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunita, Satoshi, Mori, Miki, Terada, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1993
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131158/
https://www.ncbi.nlm.nih.gov/pubmed/8438589
http://dx.doi.org/10.1006/viro.1993.1158
Descripción
Sumario:The nucleotide sequence of the 3′-end of the genomic RNA of sialodacryoadenitis virus strain 681 (SDAV-681) was determined. A large open reading frame encoding a 454-amino-acid protein was identified as the nucleocapsid protein (N) gene, since the predicted protein is similar in size, chemical properties, and amino acid sequence to the N proteins of other coronaviruses. The amino acid variance of the N proteins between SDAV and mouse hepatitis virus (MHV) is not markedly different from that among MHV strains. A high degree of genetic relatedness between SDAV and MHV was revealed in the intergenic and 3′-noncoding sequences as well as in the N gene.

Ejemplares similares