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Antiviral screening of British Columbian medicinal plants
One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the non-cytotoxic concentrations tested. The extracts of Rosa nutkana and Amelanchier alnifolia, both members of the Rosaceae, were very active a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ireland Ltd.
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131204/ https://www.ncbi.nlm.nih.gov/pubmed/8847882 http://dx.doi.org/10.1016/0378-8741(95)90037-3 |
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author | McCutcheon, A.R. Roberts, T.E. Gibbons, E. Ellis, S.M. Babiuk, L.A. Hancock, R.E.W. Towers, G.H.N. |
author_facet | McCutcheon, A.R. Roberts, T.E. Gibbons, E. Ellis, S.M. Babiuk, L.A. Hancock, R.E.W. Towers, G.H.N. |
author_sort | McCutcheon, A.R. |
collection | PubMed |
description | One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the non-cytotoxic concentrations tested. The extracts of Rosa nutkana and Amelanchier alnifolia, both members of the Rosaceae, were very active against an enteric coronavirus. A root extract of another member of the Rosaceae, Potentilla arguta, completely inhibited respiratory syncytial virus. A Sambucus racemosa branch tip extract was also very active against respiratory syncytial virus while the inner bark extract of Oplopanax horridus partially inhibited this virus. An extract of Ipomopsis aggregata demonstrated very good activity against parainfluenza virus type 3. A Lomatium dissectum root extract completely inhibited the cytopathic effects of rotavirus. In addition to these, extracts prepared from the following plants exhibited antiviral activity against herpesvirus type 1: Cardamine angulata, Conocephalum conicum, Lysichiton americanum, Polypodium glycyrrhiza and Verbascum thapsus. |
format | Online Article Text |
id | pubmed-7131204 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1995 |
publisher | Published by Elsevier Ireland Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71312042020-04-08 Antiviral screening of British Columbian medicinal plants McCutcheon, A.R. Roberts, T.E. Gibbons, E. Ellis, S.M. Babiuk, L.A. Hancock, R.E.W. Towers, G.H.N. J Ethnopharmacol Research Paper One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the non-cytotoxic concentrations tested. The extracts of Rosa nutkana and Amelanchier alnifolia, both members of the Rosaceae, were very active against an enteric coronavirus. A root extract of another member of the Rosaceae, Potentilla arguta, completely inhibited respiratory syncytial virus. A Sambucus racemosa branch tip extract was also very active against respiratory syncytial virus while the inner bark extract of Oplopanax horridus partially inhibited this virus. An extract of Ipomopsis aggregata demonstrated very good activity against parainfluenza virus type 3. A Lomatium dissectum root extract completely inhibited the cytopathic effects of rotavirus. In addition to these, extracts prepared from the following plants exhibited antiviral activity against herpesvirus type 1: Cardamine angulata, Conocephalum conicum, Lysichiton americanum, Polypodium glycyrrhiza and Verbascum thapsus. Published by Elsevier Ireland Ltd. 1995-12-01 2004-04-21 /pmc/articles/PMC7131204/ /pubmed/8847882 http://dx.doi.org/10.1016/0378-8741(95)90037-3 Text en Copyright © 1995 Published by Elsevier Ireland Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Research Paper McCutcheon, A.R. Roberts, T.E. Gibbons, E. Ellis, S.M. Babiuk, L.A. Hancock, R.E.W. Towers, G.H.N. Antiviral screening of British Columbian medicinal plants |
title | Antiviral screening of British Columbian medicinal plants |
title_full | Antiviral screening of British Columbian medicinal plants |
title_fullStr | Antiviral screening of British Columbian medicinal plants |
title_full_unstemmed | Antiviral screening of British Columbian medicinal plants |
title_short | Antiviral screening of British Columbian medicinal plants |
title_sort | antiviral screening of british columbian medicinal plants |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131204/ https://www.ncbi.nlm.nih.gov/pubmed/8847882 http://dx.doi.org/10.1016/0378-8741(95)90037-3 |
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