Identification of the active site residues in the nsP2 proteinase of sindbis virus

The nonstructural polyproteins of Sindbis virus are processed by a virus-encoded proteinase which is located in the C-terminal domain of nsP2. Here we have performed a mutagenic analysis to identify the active site residues of this proteinase. Substitution of other amino acids for either Cys-481 or...

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Detalles Bibliográficos
Autores principales: Strauss, Ellen G., De Groot, Raoul J., Levinson, Randy, Strauss, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131396/
https://www.ncbi.nlm.nih.gov/pubmed/1448929
http://dx.doi.org/10.1016/0042-6822(92)90268-T

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131396/
https://www.ncbi.nlm.nih.gov/pubmed/1448929
http://dx.doi.org/10.1016/0042-6822(92)90268-T

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