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Molecular Biology of Rubella Virus

This chapter summarizes the present medical significance of rubella virus. Rubella virus infection is systemic in nature and the accompanying symptoms are generally benign, the most pronounced being a mild rash of short duration. The most common complication of rubella virus infection is transient j...

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Autor principal: Frey, Teryl K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press Inc. Published by Elsevier Inc. 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131582/
https://www.ncbi.nlm.nih.gov/pubmed/7817880
http://dx.doi.org/10.1016/S0065-3527(08)60328-0
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author Frey, Teryl K.
author_facet Frey, Teryl K.
author_sort Frey, Teryl K.
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description This chapter summarizes the present medical significance of rubella virus. Rubella virus infection is systemic in nature and the accompanying symptoms are generally benign, the most pronounced being a mild rash of short duration. The most common complication of rubella virus infection is transient joint involvement such as polyarthralgia and arthritis. The primary health impact of rubella virus is that it is a teratogenic agent. The vaccination strategy is aimed at elimination of rubella and includes both universal vaccination of infants at 15 months of age with the trivalent measles, mumps, rubella (MMR) vaccine and specific targeting with the rubella vaccine of seronegative women planning pregnancy and seronegative adults who could come in contact with women of childbearing age, although it is recommended that any individual over the age of 12 months without evidence of natural infection or vaccination be vaccinated. Medically, the current challenge posed by rubella virus is to achieve complete vaccination coverage to prevent resurgences.
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spelling pubmed-71315822020-04-08 Molecular Biology of Rubella Virus Frey, Teryl K. Adv Virus Res Article This chapter summarizes the present medical significance of rubella virus. Rubella virus infection is systemic in nature and the accompanying symptoms are generally benign, the most pronounced being a mild rash of short duration. The most common complication of rubella virus infection is transient joint involvement such as polyarthralgia and arthritis. The primary health impact of rubella virus is that it is a teratogenic agent. The vaccination strategy is aimed at elimination of rubella and includes both universal vaccination of infants at 15 months of age with the trivalent measles, mumps, rubella (MMR) vaccine and specific targeting with the rubella vaccine of seronegative women planning pregnancy and seronegative adults who could come in contact with women of childbearing age, although it is recommended that any individual over the age of 12 months without evidence of natural infection or vaccination be vaccinated. Medically, the current challenge posed by rubella virus is to achieve complete vaccination coverage to prevent resurgences. Academic Press Inc. Published by Elsevier Inc. 1994 2008-03-02 /pmc/articles/PMC7131582/ /pubmed/7817880 http://dx.doi.org/10.1016/S0065-3527(08)60328-0 Text en © 1994 Academic Press Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Frey, Teryl K.
Molecular Biology of Rubella Virus
title Molecular Biology of Rubella Virus
title_full Molecular Biology of Rubella Virus
title_fullStr Molecular Biology of Rubella Virus
title_full_unstemmed Molecular Biology of Rubella Virus
title_short Molecular Biology of Rubella Virus
title_sort molecular biology of rubella virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131582/
https://www.ncbi.nlm.nih.gov/pubmed/7817880
http://dx.doi.org/10.1016/S0065-3527(08)60328-0
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