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Processing of the Coronavirus MHV-JHM Polymerase Polyprotein: Identification of Precursors and Proteolytic Products Spanning 400 Kilodaltons of ORF1a()

The replicase of mouse hepatitis virus strain JHM (MHV-JHM) is encoded by two overlapping open reading frames, ORF1a and ORF1b, which are translated to produce a 750-kDa precursor polyprotein. The polyprotein is proposed to be processed by viral proteinases to generate the functional replicase compl...

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Detalles Bibliográficos
Autores principales: Schiller, Jennifer J., Kanjanahaluethai, Amornrat, Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press. 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131687/
https://www.ncbi.nlm.nih.gov/pubmed/9514967
http://dx.doi.org/10.1006/viro.1997.9010