Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems

The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) r...

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Autores principales: Brun, Alejandro, Albina, Emmanuel, Barret, Tom, Chapman, David A.G., Czub, Markus, Dixon, Linda K., Keil, Günther M., Klonjkowski, Bernard, Le Potier, Marie-Frédérique, Libeau, Geneviève, Ortego, Javier, Richardson, Jennifer, Takamatsu, Haru-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131726/
https://www.ncbi.nlm.nih.gov/pubmed/18838097
http://dx.doi.org/10.1016/j.vaccine.2008.09.044
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author Brun, Alejandro
Albina, Emmanuel
Barret, Tom
Chapman, David A.G.
Czub, Markus
Dixon, Linda K.
Keil, Günther M.
Klonjkowski, Bernard
Le Potier, Marie-Frédérique
Libeau, Geneviève
Ortego, Javier
Richardson, Jennifer
Takamatsu, Haru-H.
author_facet Brun, Alejandro
Albina, Emmanuel
Barret, Tom
Chapman, David A.G.
Czub, Markus
Dixon, Linda K.
Keil, Günther M.
Klonjkowski, Bernard
Le Potier, Marie-Frédérique
Libeau, Geneviève
Ortego, Javier
Richardson, Jennifer
Takamatsu, Haru-H.
author_sort Brun, Alejandro
collection PubMed
description The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including attenuated virus and DNA and RNA viral vectors. Besides their usefulness in vaccinology, these ADSs constitute invaluable tools to researchers for understanding the nature of protective responses in different species, opening the possibility of modulating or potentiating relevant immune mechanisms involved in protection.
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spelling pubmed-71317262020-04-08 Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems Brun, Alejandro Albina, Emmanuel Barret, Tom Chapman, David A.G. Czub, Markus Dixon, Linda K. Keil, Günther M. Klonjkowski, Bernard Le Potier, Marie-Frédérique Libeau, Geneviève Ortego, Javier Richardson, Jennifer Takamatsu, Haru-H. Vaccine Review The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including attenuated virus and DNA and RNA viral vectors. Besides their usefulness in vaccinology, these ADSs constitute invaluable tools to researchers for understanding the nature of protective responses in different species, opening the possibility of modulating or potentiating relevant immune mechanisms involved in protection. Elsevier Ltd. 2008-12-02 2008-10-07 /pmc/articles/PMC7131726/ /pubmed/18838097 http://dx.doi.org/10.1016/j.vaccine.2008.09.044 Text en Copyright © 2008 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Brun, Alejandro
Albina, Emmanuel
Barret, Tom
Chapman, David A.G.
Czub, Markus
Dixon, Linda K.
Keil, Günther M.
Klonjkowski, Bernard
Le Potier, Marie-Frédérique
Libeau, Geneviève
Ortego, Javier
Richardson, Jennifer
Takamatsu, Haru-H.
Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title_full Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title_fullStr Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title_full_unstemmed Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title_short Antigen delivery systems for veterinary vaccine development: Viral-vector based delivery systems
title_sort antigen delivery systems for veterinary vaccine development: viral-vector based delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131726/
https://www.ncbi.nlm.nih.gov/pubmed/18838097
http://dx.doi.org/10.1016/j.vaccine.2008.09.044
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