Dysfunction of Cortical GABAergic Neurons Leads to Sensory Hyper-reactivity in a Shank3 Mouse Model of ASD

Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not completely understood. Here we examined the neural representations of sensory perception in the neocortex of a Shank3...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Deister, Christopher A., Gao, Xian, Guo, Baolin, Lynn-Jones, Taylor, Chen, Naiyan, Wells, Michael F., Liu, Runpeng, Goard, Michael J., Dimidschstein, Jordane, Feng, Shijing, Shi, Yiwu, Liao, Weiping, Lu, Zhonghua, Fishell, Gord, Moore, Christopher I., Feng, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131894/
https://www.ncbi.nlm.nih.gov/pubmed/32123378
http://dx.doi.org/10.1038/s41593-020-0598-6

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