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Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism
The purpose of the present study was to evaluate the anti‐cancer property of Lobetyolin on colorectal cancer and explore its potential mechanism. Lobetyolin was incubated with HCT‐116 cells in the absence or presence of ASCT2 inhibitor Benser or p53 inhibitor Pifithrin‐α. The levels of glutamine, gl...
Autores principales: | He, Wei, Tao, Weiwei, Zhang, Feng, Jie, Qian, He, Yun, Zhu, Wei, Tan, Jiani, Shen, Weixing, Li, Liu, Yang, Ye, Cheng, Haibo, Sun, Dongdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131919/ https://www.ncbi.nlm.nih.gov/pubmed/31990147 http://dx.doi.org/10.1111/jcmm.15009 |
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